New Therapeutic Strategies in Lupus Nephritis
نویسندگان
چکیده
منابع مشابه
Epidemiologic study of 40 patients with lupus nephritis in Imam Khomeini
Introduction: Systemic lupus erythematosus (SLE) is an inflammatory systemic disease that involves different organs such as heart, lungs, hematologic and musculoskletal systems, gastrointestinal tract and kidneys. Renal involvement has specific importance in disease prognosis. The present study was conducted to identify epidemiologic status, short term effects of treatment on renal involvemen...
متن کاملThe prognosis of lupus nephritis in children
Introduction: Lupus nephritis is a systemic disease which affects different organs. The present study was designed to review lupus nephritis, in children its outcome and the related factors. Methods: We reviewed 48 children with lupus nephritis. Clinical and epidemiological features were studied. The patients’ outcomes and related factors were analyzed. Patient and renal survival rate were ca...
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ABSTRACT Background: The prognosis of SLE is int1uenced by the onset of glomerulonephtitis. Clinical ttials in lupus nephritis have demonstrated that cyclophosphamide therapy is the superior regimen in the management oflupus nephritis for preserving renal function. Objective: The purpose of this study is to define the outcome of renal function with bolus pu lses of cyclophosphamide and steroid...
متن کاملClearing the complexity: immune complexes and their treatment in lupus nephritis
Systemic lupus erythematosus (SLE) is a classic antibody-mediated systemic autoimmune disease characterised by the development of autoantibodies to ubiquitous self-antigens (such as antinuclear antibodies and antidouble-stranded DNA antibodies) and widespread deposition of immune complexes in affected tissues. Deposition of immune complexes in the kidney results in glomerular damage and occurs ...
متن کاملEvaluation of Possible Role of Dendritic Cells in Various Lupus Nephritis
Background & Objectives: Chronicity of lupus nephritis (LN) should be considered for interaction of cell mediated immunity (CMI) and dendritic cells in glomeruli and tubulointerstitial areas. In this study establishment of immunohistopathological changes of dendritic cells and other immune effector cells in lupus nephritis comparing with non-lupus nephritis was performed. Materials & Methods: ...
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تاریخ انتشار 2017